Bacterial Endocarditis Aid
Prevention of Bacterial Endocarditis
Standard general prophylaxis for patients at risk:
| Amoxicillin |
2.0g given orally one hour before procedure |
Unable to take oral medication:
| Amoxicillin |
2.0g given IM or IV within 30 minutes before procedure |
Amoxicillin/Ampicillin/penicillin-allergic patient:
| Clindamycin |
600mg given orally one hour before procedure |
Cephalexin
or Cefadroxil |
2.0g orally one hour before procedure |
Azithromycin
or Clarithromycin |
500mg orally one hour before procedure |
Amoxicillin/Ampicillin/penicillin-allergic patients unable to take oral medications:
| Clindamycin |
600mg IV within 30 minutes before procedure |
| Cefazolin |
1.0g IM or IV within 30 minutes before procedure |
High-risk patients:
| Ampicillin |
Ampicillin 2.0g plus Gentamicin 1.5mg/kg |
| Gentamicin |
Not to exceed 120mg IM or IV. Complete injection/infusion within 30 minutes before starting procedure |
Moderate-risk patients:
| Amoxicillin |
2.0g orally one hour before procedure |
| Ampicillin |
2.0g IM or IV within 30 minutes before starting procedure |
Moderate-risk patients allergic to Ampicillin/Amoxicillin:
| Vancomycin |
1.0g over 1-2 hours. Complete infusion within 30 minutes of starting the procedure |
